Article
[Asporin, a susceptibility gene for osteoarthritis].
Clinical calcium - 1 Sept 2006
Ikegawa Shiro
Abstract excerpt
Osteoarthritis (OA) is the most common form of human arthritis. Genetic factors have been implicated in OA. Through a candidate gene-association study, we found association between asporin and OA. Asporin is an extracellular matrix component expressed abundantly in the articular cartilage of OA patients. A significant association between a polymorphism in the aspartic acid (D) repeat of the asporin gene (ASPN)...
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