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Article

Investigation of the asporin gene polymorphism as a risk factor for knee osteoarthritis in Iran.

American journal of orthopedics (Belle Mead, N.J.) - 1 Jul 2013

Jazayeri Roshaneak, Qoreishi Mohammad, Hoseinzadeh Hamid Reza Seyyed, Babanejad Mojgan, Bakhshi Enayatollah, Najmabadi Hossein, Jazayeri Seyyed Mohammad

Abstract excerpt

Osteoarthritis (OA) is a degenerative disease of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis. The asporin (ASPN) gene encodes a cartilage extracellular protein belonging to the small leucine-rich proteoglycan family. Polymorphisms in the aspartic acid (D) repeat region in the second exon of this gene, which consist of GAT...

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PMID: 24078942

Genes

ASPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Investigation of the asporin gene polymorphism as a risk factor for knee osteoarthritis in Iran.PMID 24078942Read ↗

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Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis.Semantic proximity Read ↗

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[Asporin, a susceptibility gene for osteoarthritis].Semantic proximity Read ↗

Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population.Semantic proximity Read ↗

Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians.Semantic proximity Read ↗

D14 repeat polymorphism of the asporin gene is associated with primary osteoarthritis of the knee in a Mexican Mestizo population.Semantic proximity Read ↗

Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.Semantic proximity Read ↗

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