Article
Conserved co-expression for candidate disease gene prioritization.
BMC bioinformatics - 23 Apr 2008
Oti Martin, van Reeuwijk Jeroen, Huynen Martijn A, Brunner Han G
Abstract excerpt
BACKGROUND: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between genes. The evolutionary conservation of co-expression between species can be used to predict protein function more reliably than co-expression in a single species. Here we examine whether co-expression across multiple species is also a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
