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Article

Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk.

BMC cancer - 23 Apr 2008

Suchy Janina, Kłujszo-Grabowska Ewa, Kładny Józef, Cybulski Cezary, Wokołorczyk Dominika, Szymańska-Pasternak Jolanta, Kurzawski Grzegorz, Scott Rodney J, Lubiński Jan

Abstract excerpt

BACKGROUND: Patients with chronic inflammatory bowel disease (IBD) are at an increased risk of colorectal cancer (CRC) and it is estimated that one in six persons diagnosed with IBD will develop CRC. This fact suggests that genetic variations in inflammatory response genes may act as CRC disease risk modifiers. METHODS: In order to test this hypothesis we investigated a series of polymorphisms in 6 genes (NOD2,...

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Identifiers

PMID: 18433468
DOI: 10.1186/1471-2407-8-112
PMCID: PMC2386482

Genes

NOD2
DLG5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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