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Article

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.

Inflammatory bowel diseases - 1 Mar 2012

Martini Maurizio, Ferrara Anna Maria, Giachelia Manuela, Panieri Emiliano, Siminovitch Katherine, Galeotti Tommaso, Larocca Luigi Maria, Pani Giovambattista

Abstract excerpt

BACKGROUND: Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (<55 years). We evaluated whether single nucleotide polymorphisms of the OCTN1 and OCTN2 genes are associated with UC, SCC, and with UC cases with cancer progression (UCCP). METHODS: We evaluated the OCTN1 and...

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PMID: 21793125
DOI: 10.1002/ibd.21814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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