Article
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.
Hepatology (Baltimore, Md.) - 1 Jun 2008
Ladeiro Yannick, Couchy Gabrielle, Balabaud Charles, Bioulac-Sage Paulette, Pelletier Laura, Rebouissou Sandra, Zucman-Rossi Jessica
Abstract excerpt
UNLABELLED: Molecular classifications defining new tumor subtypes have been recently refined with genetic and transcriptomic analyses of benign and malignant hepatocellular tumors. Here, we performed microRNA (miRNA) profiling in two series of fully annotated liver tumors to uncover associations between oncogene/tumor suppressor mutations and clinical and pathological features. Expression levels of 250 miRNAs in...
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