Article

Differential Expression of Tissue microRNAs as Diagnostic Tools for Segregating Hepatocellular Carcinoma and Cirrhosis: A Biomarker Discovery Study Using Liver Biopsy Data

2025-05-06

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is an important cause of cancer-related mortality, often arising in cirrhotic livers. Current surveillance methods, including ultrasound and serum α-fetoprotein (AFP), have limited sensitivity and specificity. Circulating microRNAs (miRNAs) have shown promise as non-invasive biomarkers, but tissue-based miRNA profiles in HCC versus cirrhosis remain underex...

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Literature Corpus work: 4618a2ed-f4ee-5be8-ac0b-7e1bcd424121
DOI: 10.20944/preprints202505.0359.v1

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