Article

Comprehensive analysis of differentially expressed miRNAs in Hepatocellular carcinoma: prognostic significance and pathway insights

2023-12-09

Abstract excerpt

Robust prognostic and predictive factors for hepatocellular carcinoma, a leading cause of cancer-related deaths worldwide, have not yet been identified. Previous studies have identified potential HCC determinants such as genetic mutations, epigenetic alterations, and pathway dysregulation. However the clinical significance of these molecular alterations remains elusive. MicroRNAs are major regulators of protein ex...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02914b33-f663-54aa-acaf-301a401b267a
DOI: 10.1101/2023.12.08.23299739

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive analysis of differentially expressed miRNAs in Hepatocellular carcinoma: prognostic significance and pathway insightsDOI 10.1101/2023.12.08.23299739Read

Screening of miRNAs as prognostic biomarkers and their associated hub targets across Hepatocellular carcinoma using survival-based bioinformatics approachSemantic proximity Read

Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinomaSemantic proximity Read

Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinomaSemantic proximity Read

MicroRNAs as biomarkers for hepatocellular carcinoma diagnosis and prognosis.Semantic proximity Read

Hepatocellular Carcinoma: The Role of MicroRNAsSemantic proximity Read

miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression.Semantic proximity Read

MicroRNAs in hepatocellular carcinoma: regulation, function, and clinical implications.Semantic proximity Read

Genome-wide analysis of genetic variations assisted by Ingenuity Pathway Analysis to comprehensively investigate potential genetic targets associated with the progression of hepatocellular carcinoma.Semantic proximity Read

Identification of diagnostic and prognostic biomarkers for cancer: Focusing on genetic variations in microRNA regulatory pathways (Review).Semantic proximity Read

Bioinformatic analysis and in vitro validation of a five-microRNA signature as a prognostic biomarker of hepatocellular carcinomaSemantic proximity Read

Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma.Semantic proximity Read

A novel microRNAs expression signature for hepatocellular carcinoma diagnosis and prognosis.Semantic proximity Read