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Molecular Classification and Novel Targets in Hepatocellular Carcinoma: Recent Advancements

1 Feb 2010

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of most lethal cancers worldwide. Strategic decisions for the advancement of molecular therapies in this neoplasm require a clear understanding of its molecular classification. Studies indicate aberrant activation of signaling pathways involved in cellular proliferation (e.g., epidermal growth factor and RAS/mitogen-activated protein kinase pathways), survival (e.g.,...

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PMID: 20175032
DOI: 10.1055/s-0030-1247131

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