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Article

Hereditary Deficiency of C3 in Animals and Humans

1 Jan 1993

Abstract excerpt

Inherited deficiency of complement C3 has been described in guinea pigs, dogs and 20 humans. Homozygous deficiency of C3 is associated with recurrent pyogenic infections by encapsulated bacteria, especially H. influenzae, S. pneumoniae and N. meningitidis. In dogs and humans there is also an association with development of glomerulonephritis of the mesangiocapillary type. Some patients also develop transient...

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Share to Adenosine and Purinergic Signaling
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Identifiers

PMID: 8340676
DOI: 10.3109/08830189309051170

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Source receipt: pubmed, retrieved 7 Sept 2026.

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