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Article

Pinched flow fractionation devices for detection of single nucleotide polymorphisms.

Lab on a chip - 1 May 2008

Larsen Asger Vig, Poulsen Lena, Birgens Henrik, Dufva Martin, Kristensen Anders

Abstract excerpt

We demonstrate a new and flexible microfluidic based method for genotyping single nucleotide polymorphisms (SNPs). The method relies on size separation of selectively hybridized polystyrene microspheres in a microfluidic pinched flow fractionation (PFF) device. The microfluidic PFF devices with 13 mum deep channels were fabricated by thermal nanoimprint lithography (NIL) in a thin film of cyclic-olefin copolymer...

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PMID: 18432355
DOI: 10.1039/b802268b

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HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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