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Microfluidic DNA microarrays in PMMA chips: streamlined fabrication via simultaneous DNA immobilization and bonding activation by brief UV exposure.

Biomedical microdevices - 1 Aug 2010

Sabourin David, Petersen Jesper, Snakenborg Detlef, Brivio Monica, Gudnadson Haukur, Wolff Anders, Dufva Martin

Abstract excerpt

This report presents and describes a simple and scalable method for producing functional DNA microarrays within enclosed polymeric, PMMA, microfluidic devices. Brief (30 s) exposure to UV simultaneously immobilized poly(T)poly(C)-tagged DNA probes to the surface of unmodified PMMA and activated the surface for bonding below the glass transition temperature of the bulk PMMA. Functionality and validation of the...

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PMID: 20336488
DOI: 10.1007/s10544-010-9420-7

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HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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