Article
The IL-6 system in HIV-1-infection and in HAART-related fat redistribution syndromes.
AIDS (London, England) - 23 Apr 2008
Saumoy Maria, López-Dupla Miguel, Veloso Sergi, Alonso-Villaverde Carlos, Domingo Pere, Broch Montserrat, Miranda Merce, Coll Blai, Saurí Amadeu, Vendrell Joan, Richart Cristóbal, Vidal Francesc
Abstract excerpt
We determined the IL-6 -174 G>C single nucleotide polymorphism, IL-6 mRNA expression in subcutaneous adipose tissue (SAT) and IL-6 plasma levels in HIV-1-infected patients with and without lipodystrophy and uninfected controls. HIV-1-infected patients had a greater prevalence of the IL-6 -174 C/C genotype and the C allele, higher SAT IL-6 mRNA expression and plasma IL-6 levels than controls. The IL-6 -174 G>C...
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