Article
Interleukin-6 gene polymorphism and lipid abnormalities in healthy subjects.
The Journal of clinical endocrinology and metabolism - 1 Mar 2000
Fernández-Real J M, Broch M, Vendrell J, Richart C, Ricart W
Abstract excerpt
Several lines of evidence indicate that interleukin-6 (IL-6) is involved not only in the hepatic acute phase response but also in adipose tissue metabolism, lipoprotein lipase activity, and hepatic triglyceride secretion. A polymorphism in the IL-6 gene, associated with differences in IL-6 transcription rate, has been recently described. We aimed to study whether this IL-6 gene polymorphism leads to differences...
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