Article
The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.
BMC microbiology - 26 Aug 2010
Forslund Anna-Lena, Salomonsson Emelie Näslund, Golovliov Igor, Kuoppa Kerstin, Michell Stephen, Titball Richard, Oyston Petra, Noppa Laila, Sjöstedt Anders, Forsberg Ake
Abstract excerpt
BACKGROUND: All four Francisella tularensis subspecies possess gene clusters with potential to express type IV pili (Tfp). These clusters include putative pilin genes, as well as pilB, pilC and pilQ, required for secretion and assembly of Tfp. A hallmark of Tfp is the ability to retract the pilus...
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