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Article

Variable number of tandem repeats polymorphism in parathyroid hormone-related protein as predictor of peak bone mass in young healthy Finnish males.

European journal of endocrinology - 1 May 2008

Gupta Ajay, Välimäki Ville-Valtteri, J Välimäki Matti, Löyttyniemi Eliisa, Richard Marilyn, L Bukka Prasanna, Goltzman David, Karaplis Andrew C

Abstract excerpt

OBJECTIVE: Mice with osteoblast-specific deletion of parathyroid hormone-related protein (PTHrP) exhibit impaired recruitment and increased apoptosis of osteogenic cells resulting in decreased bone formation and premature osteoporosis. The PTHrP levels within the bone microenvironment are therefore critical in influencing bone mass acquisition. Whether this is applicable in humans has not been established. Here,...

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Identifiers

PMID: 18426836
DOI: 10.1530/EJE-07-0886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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