Article
Steroid hormone receptor gene polymorphisms and osteoporosis: a pharmacogenomic review.
Expert opinion on pharmacotherapy - 1 Apr 2007
Gennari Luigi, De Paola Vincenzo, Merlotti Daniela, Martini Giuseppe, Nuti Ranuccio
Abstract excerpt
Osteoporosis is a common skeletal disorder with a strong genetic component. In recent years, significant progress has been made in understanding the genetic basis of osteoporosis. Given the biological significance of signalling through steroid hormone receptors, bone biology and calcium homeostasis, alleles of steroid hormone receptor genes have been postulated to contribute to the well-documented genetic...
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