Article
Association between promoter region genetic variants of PTH SNPs and serum 25(OH)-vitamin D level.
International journal of clinical and experimental pathology - 1 Jan 2015
Al-Daghri Nasser M, Al-Attas Omar S, Krishnaswamy Soundararajan, Yakout Sobhy M, Mohammed Abdul Khader, Alenad Amal M, Chrousos George P, Alokail Majed S
Abstract excerpt
Parathyroid hormone (PTH) plays a crucial role in calcium metabolism and skeletal development via altering vitamin D level. Besides, hypersecretion of PTH is implicated in the etiology of osteoporosis. In this study, we analyzed association between promoter region sequence variants of PTH gene and circulating 25-hydroxy-vitamin D (25(OH)D) level. Genotypes of PTH SNPs rs1459015, rs10500783 and rs10500784 and...
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