Article
Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2009
Wang Y, Samuels J F, Chang Y C, Grados M A, Greenberg B D, Knowles J A, McCracken J T, Rauch S L, Murphy D L, Rasmussen S A, Cullen B, Hoehn-Saric R, Pinto A, Fyer A J, Piacentini J, Pauls D L, Bienvenu O J, Riddle M, Shugart Y Y, Liang K Y, Nestadt G
Abstract excerpt
Several clinical and genetic studies have reported gender differences in obsessive-compulsive disorder (OCD). Previously, we conducted a linkage genome scan using multipoint allele-sharing methods to test for linkage in 219 families participating in the OCD Collaborative Genetics Study. When these families were stratified by proband's gender, suggestive linkage to chromosome 11p15 at marker D11S2362 (KAC(all) =...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.