Article
Genome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36.
Biological psychiatry - 15 Oct 2012
Mathews Carol A, Badner Judith A, Andresen J Michael, Sheppard Brooke, Himle Joseph A, Grant Jon E, Williams Kyle A, Chavira Denise A, Azzam Amin, Schwartz Maxine, Reus Victor I, Kim Suck Won, Cook Edwin H, Hanna Gregory L
Abstract excerpt
BACKGROUND: Obsessive-compulsive disorder (OCD) has a complex etiology involving both genetic and environmental factors. However, the genetic causes of OCD are largely unknown, despite the identification of several promising candidate genes and linkage regions. METHODS: Our objective was to conduct genetic linkage studies of the type of OCD thought to have the strongest genetic etiology (i.e., childhood-onset...
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