Article
Homeobox genes in obsessive-compulsive disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2012
Nestadt G, Wang Y, Grados M A, Riddle M A, Greenberg B D, Knowles J A, Fyer A J, McCracken J T, Rauch S L, Murphy D L, Rasmussen S A, Cullen B, Piacentini J, Geller D, Pauls D, Bienvenu O J, Chen Y, Liang K Y, Goes F S, Maher B, Pulver A E, Shugart Y Y, Valle D, Samuels J F, Chang Y C
Abstract excerpt
BACKGROUND: Despite evidence that obsessive-compulsive disorder (OCD) is a familial neuropsychiatric condition, progress aimed at identifying genetic determinants of the disorder has been slow. The OCD Collaborative Genetics Study (OCGS) has identified several OCD susceptibility loci through linkage analysis. METHODS: In this study we investigate two regions on chromosomes 15q and 1q by first refining the linkage...
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