Article
'Unique' alleles in admixed populations: a strategy for determining 'hereditary' population differences of disease frequencies.
Ethnicity & disease - 1 Jan 1991
Chakraborty R, Kamboh M I, Ferrell R E
Abstract excerpt
The genetic contribution of a parental population in an admixed population can be estimated from the frequencies of unique alleles that exist only in that parental population. In this work we show that although the estimated admixture component from a single such unique allele may be quite unstable, when multiple numbers of unique alleles are recognized, they together allow precise estimation of admixture...
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