Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution

Abstract excerpt

The admixture model is widely applied to estimate and interpret population structure among individuals. Here we consider a “standard admixture” model that assumes the admixed populations are unrelated and also a generalized model, where the admixed populations themselves are related via coancestry (or covariance) of allele frequencies. The generalized model yields a potentially more realistic and substantially mor...

Topics

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• Algorithms
• Computational Biology
• Computer Simulation
• Gene Frequency
• Genetics, Population
• Models, Genetic
• Models, Statistical
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

04368959-3eb0-53a4-b1e7-d8216c63623a

DOI

10.1101/2024.12.29.630632