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Article

A novel mouse model of X-linked cardiac hypertrophy.

American journal of physiology. Heart and circulatory physiology - 1 Jun 2008

Leatherbury L, Yu Q, Chatterjee B, Walker D L, Yu Z, Tian X, Lo C W

Abstract excerpt

We recovered a novel mouse mutant exhibiting neonatal lethality associated with severe fetal cardiac hypertrophy and with some adult mice dying suddenly with left ventricular hypertrophic cardiomyopathy. Using Doppler echocardiography, we screened surviving adult mice in this mutant line for cardiac hypertrophy. Cardiac dimensions were obtained either from two-dimensional images collected using a novel ECG-gated...

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Share to Genetic Diseases, X-Linked
Share to Heart Ventricles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertrophy, Left Ventricular

Share to Mitochondria, Heart

Share to Myocardial Contraction

Share to Sarcoplasmic Reticulum

Share to Stroke Volume

Share to Ventricular Function, Left

Source

Identifiers

PMID: 18424640
DOI: 10.1152/ajpheart.00160.2007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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