Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death.

Eukaryotic cell - 1 Sept 2013

Langford Melanie L, Hargarten Jessica C, Patefield Krista D, Marta Elizabeth, Blankenship Jill R, Fanning Saranna, Nickerson Kenneth W, Atkin Audrey L

Abstract excerpt

Quorum sensing by farnesol in Candida albicans inhibits filamentation and may be directly related to its ability to cause both mucosal and systemic diseases. The Ras1-cyclic AMP signaling pathway is a target for farnesol inhibition. However, a clear understanding of the downstream effectors of the morphological farnesol response has yet to be unraveled. To address this issue, we screened a library for mutants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Hot Temperature

Share to Mutation

Share to Quorum Sensing

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23873867
DOI: 10.1128/EC.00311-12
PMCID: PMC3811573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death.PMID 23873867Read ↗

Farnesol signalling in Candida albicans – more than just communicationSemantic proximity Read ↗

Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis.Semantic proximity Read ↗

Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction.Semantic proximity Read ↗

Properties and role of the quorum sensing molecule farnesol in relation to the yeast Candida albicansSemantic proximity Read ↗

Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens.Semantic proximity Read ↗

Deciphering the molecular components of the quorum sensing system in the fungus Ophiostoma piceaeSemantic proximity Read ↗

Farnesol and phosphorylation of the transcriptional regulator Efg1 affect Candida albicans white-opaque switching rates.Semantic proximity Read ↗

Quorum sensing in fungi – a reviewSemantic proximity Read ↗

Expression of the Candida albicans morphogenesis regulator gene CZF1 and its regulation by Efg1p and Czf1p.Semantic proximity Read ↗

Functional mapping of the Candida albicans Efg1 regulator.Semantic proximity Read ↗

Impact of a Cross-Kingdom Signaling Molecule of Candida albicans on Acinetobacter baumannii PhysiologySemantic proximity Read ↗

Modulation of Morphogenesis in Candida albicans by Various Small MoleculesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.