Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporally expressed PDGF and FGF-2 regulate embryonic coronary artery formation and growth.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2008

Tomanek Robert J, Hansen Heidi K, Christensen Lance P

Abstract excerpt

OBJECTIVE: PDGF and FGF-2 are important regulators of vascular wall assembly. We tested the hypothesis that their embryonic temporal expression facilitates 2 specific events: (1) the endothelial invasion of the aortic root to form the coronary artery stems and (2) the subsequent growth and development of the arterial tree. METHODS AND RESULTS: Addition of FGF-2 and PDGF-BB proteins to embryonic quail heart...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis Inhibitors
Share to Becaplermin
Share to Coronary Vessels

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Platelet-Derived Growth Factor

Share to Proto-Oncogene Proteins c-sis

Share to Tissue Culture Techniques

Share to Vascular Endothelial Growth Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 18420995
DOI: 10.1161/ATVBAHA.108.166454
PMCID: PMC2748328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporally expressed PDGF and FGF-2 regulate embryonic coronary artery formation and growth.PMID 18420995Read ↗

Coronary Artery Development: Origin, Malformations, and Translational Vascular Reparative Therapy.Semantic proximity Read ↗

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.Semantic proximity Read ↗

Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4Semantic proximity Read ↗

CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heartSemantic proximity Read ↗

Phylogeny informs ontogeny: a proposed common theme in the arterial pole of the vertebrate heartSemantic proximity Read ↗

Angiopoietin 1 expression levels in the myocardium direct coronary vessel development.Semantic proximity Read ↗

Coronary artery and orifice development is associated with proper timing of epicardial outgrowth and correlated Fas-ligand-associated apoptosis patterns.Semantic proximity Read ↗

Fast revascularization of the injured area is essential to support zebrafish heart regeneration.Semantic proximity Read ↗

Vegfaa instructs cardiac muscle hyperplasia in adult zebrafishSemantic proximity Read ↗

Abnormal myocardial and coronary vasculature development in experimental hypoxia.Semantic proximity Read ↗

Does the subepicardial mesenchyme contribute myocardioblasts to the myocardium of the chick embryo heart? A quail‐chick chimera study tracing the fate of the epicardial primordiumSemantic proximity Read ↗

Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.