Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish

Abstract excerpt

Significance The human heart is unable to meaningfully recover lost cardiac muscle after injury. As a result, injuries such as myocardial infarction cause irreversible damage that increases the risk for heart failure. Replacing lost or dysfunctional cardiac tissue can potentially reverse or prevent heart failure. Here we demonstrate that experimentally increasing expression of the angiogenic factor vegfaa alone...

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