Article
Fast revascularization of the injured area is essential to support zebrafish heart regeneration.
Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2016
Marín-Juez Rubén, Marass Michele, Gauvrit Sebastien, Rossi Andrea, Lai Shih-Lei, Materna Stefan C, Black Brian L, Stainier Didier Y R
Abstract excerpt
Zebrafish have a remarkable capacity to regenerate their heart. Efficient replenishment of lost tissues requires the activation of different cell types including the epicardium and endocardium. A complex set of processes is subsequently needed to support cardiomyocyte repopulation. Previous studies have identified important determinants of heart regeneration; however, to date, how revascularization of the damaged...
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