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Article

Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction.

Stem cells (Dayton, Ohio) - 1 Jul 2008

Roussa Eleni, Oehlke Oliver, Rahhal Belal, Heermann Stephan, Heidrich Stefanie, Wiehle Michael, Krieglstein Kerstin

Abstract excerpt

The aim of the present study was to investigate the putative cooperative effects of transforming growth factor beta (TGF-beta) and glial cell line-derived neurotrophic factor (GDNF) family ligands in the differentiation of midbrain progenitors toward a dopaminergic phenotype. Therefore, a mouse midbrain embryonic day (E) 12 neurospheres culture was used as an experimental model. We show that neurturin and...

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Source

Identifiers

PMID: 18420832
DOI: 10.1634/stemcells.2007-0805

Genes

GDNF
PSPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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