Article
PrP genotypes of free-ranging wapiti (Cervus elaphus nelsoni) with chronic wasting disease.
The Journal of general virology - 1 May 2008
Perucchini Matteo, Griffin Karen, Miller Michael W, Goldmann Wilfred
Abstract excerpt
Variation in PrP prion gene sequence appears to modulate susceptibility to chronic wasting disease (CWD), a naturally occurring prion disease affecting four North American species of the family Cervidae. Wapiti (Cervus elaphus nelsoni) PrP is polymorphic at codon 132 [methionine (M) or leucine (L)]. We genotyped 171 samples, collected between 2002 and 2005 from CWD-infected and uninfected wapiti from three...
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