Article
PrP genotypes of captive and free-ranging Rocky Mountain elk (Cervus elaphus nelsoni) with chronic wasting disease.
The Journal of general virology - 1 Oct 1999
O'Rourke K I, Besser T E, Miller M W, Cline T F, Spraker T R, Jenny A L, Wild M A, Zebarth G L, Williams E S
Abstract excerpt
The PrP gene encodes the putative causative agent of the transmissible spongiform encephalopathies (TSEs), a heterogeneous group of fatal, neurodegenerative disorders including human Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, ovine scrapie and chronic wasting disease (CWD) of North American deer and elk. Polymorphisms in the PrP gene are associated with variations in relative susceptibility,...
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