Article
Estimating relative CWD susceptibility and disease progression in farmed white-tailed deer with rare PRNP alleles.
PloS one - 1 Jan 2019
Haley Nicholas J, Merrett Kahla, Buros Stein Amy, Simpson Dennis, Carlson Andrew, Mitchell Gordon, Staskevicius Antanas, Nichols Tracy, Lehmkuhl Aaron D, Thomsen Bruce V
Abstract excerpt
Chronic wasting disease is a prion disease affecting both free-ranging and farmed cervids in North America and Scandinavia. A range of cervid species have been found to be susceptible, each with variations in the gene for the normal prion protein, PRNP, reportedly influencing both disease susceptibility and progression in the respective hosts. Despite the finding of several different PRNP alleles in white-tailed...
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