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Article

The tail of mycolic acids.

Chemistry & biology - 1 Apr 2008

Lu Jeff Zhiqiang, Prigge Sean T

Abstract excerpt

The FabH enzyme from M. tuberculosis binds the acyl tail of large substrates at the end of a buried hydrophobic tunnel. Sachdeva et al. (2008) use reactive chemical probes and X-ray crystallography to show that substrates can bind to an open state of FabH without threading through the tunnel.

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Identifiers

PMID: 18420136
DOI: 10.1016/j.chembiol.2008.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18420136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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