Article
Characterization of an asporogenous mutant of Streptomyces aureofaciens with increased resistance to several aminoglycoside antibiotics.
Folia microbiologica - 1 Jan 1991
Weiser J, Stastná J, Morava P, Cáslavská J, Novotná J
Abstract excerpt
An asporogenous spontaneous mutant of Streptomyces aureofaciens named ASR1 was selected on streptomycin gradient plates. The mutant is very stable and differs in ultrastructure and morphology, it is prototrophic but it lost the ability to grow well on soybean extract medium and produces one-tenth tetracyclines of the parent. The ASR1 mutant has a 3-4-fold increased resistance to streptomycin and is...
Topics
- Aminoglycosides
- Anti-Bacterial Agents
- Bacterial Proteins
- Drug Resistance, Microbial
- Mutation
- Spores, Bacterial
- Streptomyces aureofaciens
- Tetracycline