Article
SCO6992, a Protein with β-Glucuronidase Activity, Complements a Mutation at the absR Locus and Promotes Antibiotic Biosynthesis in Streptomyces coelicolor.
Journal of microbiology and biotechnology - 28 Nov 2021
Jin Xue-Mei, Choi Mu-Yong, Tsevelkhoroloo Maral, Park Uhnmee, Suh Joo-Won, Hong Soon-Kwang
Abstract excerpt
Streptomyces coelicolor is a filamentous soil bacterium producing several kinds of antibiotics. S. coelicolor abs8752 is an abs (antibiotic synthesis deficient)-type mutation at the absR locus; it is characterized by an incapacity to produce any of the four antibiotics synthesized by its parental strain J1501. A chromosomal DNA fragment from S. coelicolor J1501, capable of complementing the abs- phenotype of the...
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