Article
Human parainfluenza virus type 2 V protein inhibits genome replication by binding to the L protein: possible role in promoting viral fitness.
Journal of virology - 1 Jul 2008
Nishio Machiko, Ohtsuka Junpei, Tsurudome Masato, Nosaka Tetsuya, Kolakofsky Daniel
Abstract excerpt
The human parainfluenza virus type 2 (hPIV2) V protein plays important roles in inhibiting the host interferon response and promoting virus growth, but its role in hPIV2 replication and transcription is not clear. A green fluorescent protein (GFP)-expressing a negative-sense minigenomic construct of hPIV2 has been established by standard technology, with helper plasmids expressing the nucleocapsid protein (NP),...
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