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Sulfatide Is Required for Efficient Replication of Influenza A Virus

17 Apr 2008

Abstract excerpt

Sulfatide is abundantly expressed in various mammalian organs, including the intestines and trachea, in which influenza A viruses (IAVs) replicate. However, the function of sulfatide in IAV infection remains unknown. Sulfatide is synthesized by two transferases, ceramide galactosyltransferase (CGT) and cerebroside sulfotransferase (CST), and is degraded by arylsulfatase A (ASA). In this study, we demonstrated...

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PMID: 18417587
DOI: 10.1128/jvi.02496-07

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