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Article

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses.

PloS one - 1 Jan 2013

Job Emma R, Bottazzi Barbara, Gilbertson Brad, Edenborough Kathryn M, Brown Lorena E, Mantovani Alberto, Brooks Andrew G, Reading Patrick C

Abstract excerpt

Members of the pentraxin family, including PTX3 and serum amyloid P component (SAP), have been reported to play a role in innate host defence against a range of microbial pathogens, yet little is known regarding their antiviral activities. In this study, we demonstrate that human SAP binds to human influenza A virus (IAV) strains and mediates a range of antiviral activities, including inhibition of IAV-induced...

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Source

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Identifiers

PMID: 23544079
DOI: 10.1371/journal.pone.0059623
PMCID: PMC3609861

Genes

PTX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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