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Article

Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis

28 Mar 2019

Abstract excerpt

Influenza virus is the pathogen responsible for the second largest pandemic in human history. A better understanding of how influenza virus enters host cells may lead to the development of more-efficacious therapies against emerging strains of the virus. Here we show that the glycosphingolipid metabolizing enzyme glucosylceramidase is required for optimal influenza virus trafficking to late endosomes and for...

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PMID: 30918081
DOI: 10.1128/jvi.00017-19

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