Article
The impact of common genetic variations in genes of the sex hormone metabolic pathways on steroid hormone levels and prostate cancer aggressiveness.
Cancer prevention research (Philadelphia, Pa.) - 1 Dec 2011
Sun Tong, Oh William K, Jacobus Susanna, Regan Meredith, Pomerantz Mark, Freedman Matthew L, Lee Gwo-Shu Mary, Kantoff Philip W
Abstract excerpt
Our previous work suggested that there was no significant association between plasma steroid hormone levels and prostate cancer tumor grade at diagnosis. In this study, we systematically tested the hypothesis that inherited variations in the androgen and estrogen metabolic pathways may be associated with plasma levels of steroid hormones, or prostate cancer aggressiveness at diagnosis. Plasma hormone levels...
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