Article
Genetic influences on bone loss in the San Antonio Family Osteoporosis study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Dec 2008
Shaffer J R, Kammerer C M, Bruder J M, Cole S A, Dyer T D, Almasy L, MacCluer J W, Blangero J, Bauer R L, Mitchell B D
Abstract excerpt
UNLABELLED: The genetic contribution to age-related bone loss is not well understood. We estimated that genes accounted for 25-45% of variation in 5-year change in bone mineral density in men and women. An autosome-wide linkage scan yielded no significant evidence for chromosomal regions implicated in bone loss. INTRODUCTION: The contribution of genetics to acquisition of peak bone mass is well documented, but...
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