Article
Mapping genes for osteoporosis--old dogs and new tricks.
Bone - 1 May 2010
Duncan Emma L, Brown Matthew A
Abstract excerpt
In stark contrast to its horticultural origins, modern genetics is an extremely technology-driven field. Almost all the major advances in the field over the past 20 years have followed technological developments that have permitted change in study designs. The development of PCR in the 1980s led to RFLP mapping of monogenic diseases. The development of fluorescent-tagged genotyping methods led to linkage mapping...
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