Article
Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 2008
Chen Han-Chun, Hu Wei-Xin, Liu Qing-Xia, Li Wen-Kai, Chen Fang-Zhi, Rao Zhou-Zhou, Liu Xin-Fa, Luo Ya-Ping, Cao Yan-Fei
Abstract excerpt
The genetic polymorphisms of biotransformation phase I enzymes, cytochrome P450 (CYP1A1 and CYP2D6), and phase II enzymes, glutathione S-transferase (GSTM1 and GSTT1), were analyzed in 204 healthy persons and 348 leukemia patients, who suffered from also acute lymphoblastic leukemia (ALL), acute nonlymphoblastic leukemia (ANLL) chronic myelogenous leukemia (CML), from the Han ethnic group in Changsha City of...
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