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Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathway

7 Apr 2008

Abstract excerpt

Gastric carcinogenesis is a complex, multistep and multifactorial event, characterized by progressive cyto-histological dedifferentiation, in which the role of Helicobacter pylori infection has been established. Among the pathways relevant to gastric carcinogenesis and correlated with H. pylori infection, it has been demonstrated that the production of reactive oxygen species, with damage to the DNA, may be quite...

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PMID: 18414189
DOI: 10.1097/cej.0b013e3282f0bff5

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