Article
At the bedside: Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer.
Journal of leukocyte biology - 1 Aug 2014
Dalal Rahul S, Moss Steven F
Abstract excerpt
Clinical trials performed in populations at high GC risk have demonstrated that eradication of Helicobacter pylori from the stomach with a course of combination antimicrobials helps prevent gastric carcinogenesis when they are administered before precancerous lesions have yet developed. In this review, we consider the insights into H. pylori-associated gastric carcinogenesis that have been gained from these and...
Topics
- DNA Damage
- Genetic Predisposition to Disease
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Inflammation
- Polymorphism, Single Nucleotide
- Stomach Neoplasms
