Article
From gastric inflammation to gastric cancer.
Digestive diseases (Basel, Switzerland) - 1 Jan 2010
Bornschein Jan, Kandulski Arne, Selgrad Michael, Malfertheiner Peter
Abstract excerpt
The majority of gastric adenocarcinomas are related to chronic inflammation induced by Helicobacter pylori infection. For intestinal-type gastric cancer, a multistep process of mucosal alterations leading from gastritis via glandular atrophy, intestinal metaplasia and dysplasia to invasive carcinoma is well recognized. Ongoing clinical studies focus on a 'point of no return'. It is defined as a situation when...
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