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<i>Helicobacter pylori</i> and Epigenetic Mechanisms Underlying Gastric Carcinogenesis

1 Jan 2007

Abstract excerpt

Gastric carcinogenesis is a multistep process triggered by Helicobacter pylori and characterized by accumulation of molecular alterations. Two mechanisms are implicated in cancer-related molecular alterations: genetic and epigenetic. The former includes changes in the DNA sequence, the latter occurs without changes of DNA sequence. However, the most important difference between genetic and epigenetic alterations...

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PMID: 17827945
DOI: 10.1159/000103890

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