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Article

Genetic variation in the inhibin pathway and risk of testicular germ cell tumors.

Cancer research - 15 Apr 2008

Purdue Mark P, Graubard Barry I, Chanock Stephen J, Rubertone Mark V, Erickson Ralph L, McGlynn Katherine A

Abstract excerpt

Gene-knockout studies in mice suggest that INHA, encoding a subunit of gonadotropin-regulating proteins known as inhibins, is a tumor suppressor for testicular stromal cell tumors. It is not known whether genetic variation in the inhibin pathway also influences susceptibility to testicular germ cell tumors (TGCT), the most common testicular cancer in young men. To address this question, we conducted a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18413775
DOI: 10.1158/0008-5472.CAN-07-5852
PMCID: PMC2997349

Genes

INHA
INHBA
INHBB
INHBC
INHBE
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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