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Novel and Highly Recurrent Chromosomal Alterations in Sezary Syndrome

15 Apr 2008

Abstract excerpt

This study was designed to identify highly recurrent genetic alterations typical of Sézary syndrome (Sz), an aggressive cutaneous T-cell lymphoma/leukemia, possibly revealing pathogenetic mechanisms and novel therapeutic targets. High-resolution array-based comparative genomic hybridization was done on malignant T cells from 20 patients. Expression levels of selected biologically relevant genes residing within...

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PMID: 18413736
DOI: 10.1158/0008-5472.can-07-6398

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