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Article

Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome.

The Journal of investigative dermatology - 1 Jul 2016

Prasad Aparna, Rabionet Raquel, Espinet Blanca, Zapata Luis, Puiggros Anna, Melero Carme, Puig Anna, Sarria-Trujillo Yaris, Ossowski Stephan, Garcia-Muret Maria P, Estrach Teresa, Servitje Octavio, Lopez-Lerma Ingrid, Gallardo Fernando, Pujol Ramon M, Estivill Xavier

Abstract excerpt

Sézary syndrome is a leukemic form of cutaneous T-cell lymphoma with an aggressive clinical course. The genetic etiology of the disease is poorly understood, with chromosomal abnormalities and mutations in some genes being involved in the disease. The goal of our study was to understand the genetic basis of the disease by looking for driver gene mutations and fusion genes in 15 erythrodermic patients with...

Read the complete abstract on PubMed

Topics

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Share to Chromosome Aberrations
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Duplication

Share to Lymphoma, T-Cell, Cutaneous

Share to Oncogene Proteins, Fusion

Share to Sequence Analysis, RNA

Share to Skin Neoplasms

Source

Identifiers

PMID: 27039262
DOI: 10.1016/j.jid.2016.03.024

Genes

RASA2
BCR
CBLB
DAD1
DSC1
FASN
ITPR1
ITPR2
NFKB2
RAG2
RAMP3
RIPK2
SGMS1
TBRG4
TYK2
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome.PMID 27039262Read ↗

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